How much does Mounjaro cost in the UK?

We know sudden medication price rises can be stressful and disruptive, especially when you’ve built momentum with your weight loss journey.

From 1 September 2025, Eli Lilly, the manufacturer of Mounjaro (tirzepatide), will increase its UK list price to align with other developed countries. This nationwide change applies to providers including pharmacies, private clinics, and digital platforms.

In response, we’ve lowered the price of our Wegovy programme by 25%, and we’re making it easier for patients to switch without starting over, so that effective treatment remains within reach for as many people as possible.

Mounjaro vs Wegovy for weight loss

Both Mounjaro and Wegovy are once-weekly GLP-1 injections that work by reducing appetite and supporting weight loss. The key difference is: Wegovy contains semaglutide, a GLP-1 that’s been used by over 8 million people worldwide and studied in more than 39,000 clinical trial participants. Mounjaro contains tirzepatide.

Both of these medications are considered the gold standard when it comes to aiding weight loss efforts. Thus far, the two medications haven't been directly compared to each other in medical trials.

It's long been thought that Mounjaro leads to more significant weight loss outcomes than Wegovy but with recent research, that is changing.

In clinical trials, patients on the highest possible dose of Wegovy lost up to 20.7% of their body weight, compared to 20.9% with Mounjaro at its highest dose — showing that both can be highly effective when used consistently and with the right support [6][7]. This higher dose of Wegovy isn’t available just yet, but it’s expected to launch in the UK soon.

With Juniper, Wegovy is delivered as part of a complete programme that includes expert care, coaching, and tracking tools — to help you get the most from your treatment.

Can I switch from Mounjaro to Wegovy?

Yes! It is both safe and straightforward to switch from Mounjaro to Wegovy. To begin, please contact your healthcare provider to discuss the transition process.

If you've decided to move medication providers, you can inform your new prescriber of what weight loss medications and dosages you're using and they'll be able to advise you on next steps.

At Juniper, you simply need to answer some quick questions about your medical history and goals, then choose whether to continue on your current medication or switch to an equivalent dosage in the same trusted GLP-1 class of medications.

It's important to note that Wegovy and Mounjaro aren't interchangeable medications, so there is a short period of time where you come off one before starting the other. However, we only require a 7-day gap between your last Mounjaro dose and your first Wegovy dose — unlike most providers, who require 28 days.

And, if you've recently been on Mounjaro, you'll likely be able to start Wegovy at a higher dose, rather than beginning from scratch. Your Juniper clinician will review your treatment history and be able to advise on your circumstances.

Juniper’s clinical switching protocol is designed to make the change simple and safe:

• ‍Review — Your clinician assesses your treatment history and dose tolerance.‍
• Match — If eligible, you start on an equivalent high dose to avoid losing progress.‍
• Transition — Only a 7-day window is required between your last Mounjaro dose and your first Wegovy dose (most providers require 28 days).‍
• Support — Pharmacist check-ins, dose adjustments, and lifestyle guidance keep you on track.

Wegovy cost with Juniper

How does Mounjaro work?

Mounjaro contains the active ingredient tirzepatide, which comes from a class of drugs called GLP-1 agonists. When you consume food, your gut releases a hormone called GLP-1 (glucagon-like peptide-1) that helps the body regulate hunger and blood sugar levels.

Medications like Mounjaro, Wegovy, and Saxenda all try to mimic the actions of this GLP-1 hormone. Where Mounjaro differs, however, is that it also mimics another hormone: glucose-dependent insulinotropic polypeptide (GIP).

GLP-1s work by improving insulin function to lower blood sugar levels, as well as delaying gastric emptying, which then serves to decrease appetite. They also communicate with the brain’s appetite control centre — the hypothalamus — to reduce food-seeking behaviour. 

In addition, GIP is a hormone released in response to food that helps fat cells to 'absorb' more excess energy, preventing fat from being stored in the liver or pancreas. It also helps to regulate blood sugar levels.

As a result, Mounjaro helps to reduce appetite which can make individuals feel fuller for longer. It’s for this reason that those taking the medication often report eating fewer calories, with reduced calorie intake being an essential part of any weight loss programme.

According to a 2021 study, participants who took Mounjaro reported sharper reductions in blood sugar levels and greater weight loss than those taking Wegovy and Ozempic [1].

Mounjaro is taken weekly via injection, with patients typically starting on a 2.5mg-dose injection once weekly for 4 weeks.

As appetite becomes better regulated, patients find they have greater control in sticking to a diet, which has led the drug to be hailed as an effective weight loss tool, especially when combined with regular exercise and a balanced diet.

Are there any side effects of taking Mounjaro for weight loss?

Mounjaro may be effective for weight loss, but that doesn't mean it's not without its side effects. The most common side effects reported by those taking a Mounjaro prescription include feelings of nausea, diarrhoea, decreased appetite, vomiting, constipation, and indigestion due to the medication's impact on the digestive system [3].

These side effects were typically experienced around the time of injection and when you increase your dosage, with most patients finding their body adjusted and side effects eased off with continued treatment. In rare instances, the drug can lead to renal failure, pancreatitis, hypoglycemia, and gastrointestinal bleeding.

Mounjaro also comes with a boxed warning, which refers to the most serious warning offered by the Food and Drug Administration. According to the FDA, using Mounjaro may increase your risk of developing thyroid cancer. For those with a family member or history of any kind of thyroid cancer, doctors are unlikely to prescribe the medication.

Despite this, it's important to remember that everyone responds differently to medications, with some experiencing no side effects while others might encounter persistent issues. Make sure to chat with your healthcare provider to ensure this treatment is the right choice for you.

If you're thinking of giving Mounjaro a go, here's what you need to know about where it's available in the UK and how much it will set you back.

How much does Mounjaro cost?

Mounjaro is a medication option offered in the Juniper Programme, starting from £189 monthly.

With the Juniper Programme, you can access weight loss medication tailored to your health and goals — never one-size-fits-all. Our app helps you track progress, connect with your care team, adjust medication as needed, and access expert support. You'll also get structured tools to build lasting habits and ongoing care.

We help you make lifestyle and habit changes, and we’re in it with you for the long run, having helped thousands of women achieve their weight loss goals.

Can I get Mounjaro on the NHS?

Yes, Mounjaro is available on the NHS for weight loss and can now be obtained at GP surgeries in England. Previously, only Wegovy and Saxeda were available on the NHS, however these could only be accessed with a referral to an NHS specialist weight management service.  

It’s important to note that while GPs can now prescribe Mounjaro, access is extremely limited and the eligibility criteria is incredibly strict. As such, officials are asking people to not approach their GPs about the weight loss medication unless they meet the following criteria:

Year 1

• BMI ≥ 40 (or ≥ 37.5 for some ethnic groups)
• 4 or more weight-related comorbidities (e.g. type 2 diabetes, high blood pressure, sleep apnoea)‍

‍Year 2

• BMI 35 to 39.9
• Still require 4 or more co-morbidities‍

‍‍Year 3

• BMI ≥ 40
• 3 or more co-morbidities

This staged approach will reach 220,000 patients across the first three years. A full rollout is planned over 8 further years, eventually covering patients with BMI ≥ 35 and at least one comorbidity.

Where can I buy Mounjaro in the UK?

Both Mounjaro and Wegovy are available via the Juniper Programme, allowing you to choose which medication — either GIP and GLP-1 with Mounjaro, or GLP-1 with Wegovy — in conjunction with your doctor. For those looking to start their weight loss journey, support is critical from clinical experts and treatment programmes.

Offering a medical approach to losing weight that sees the average patient lose up to 20% of their body weight in one year, the Juniper Programme is tailored to you. Designed by clinicians and dietitians, our programme works to effectively suppress appetite and improve metabolic function.

Consider it a new era in weight loss, one that understands it's never about just the number on the scale but the confidence, energy and control you feel, too.

Photo credit: Ketut Subiyanto / Pexels