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Non-surgical weight loss: Your guide to the most effective options

What you need to know about surgical and non-surgical weight loss procedures.

Written by Lucinda Starr
|
Reviewed by Kevin Joshua, BSc, MRSPH
Last updated Jul 28, 2025
5 min read
12 References
Your Complete Guide to Non-Surgical Weight Loss | Juniper
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Key takeaways

  • While surgical options like gastric balloon, gastric sleeve, and gastric band are effective for weight loss, non-surgical methods, including lifestyle changes and weight loss medications like Wegovy and Mounjaro, can also deliver significant results without invasive procedures.
  • Weight loss is impacted by various factors, including diet, exercise, metabolism, hormones, and lifestyle choices. Addressing these holistically, alongside medical treatments if needed, can lead to sustainable weight loss.
  • Wegovy and Mounjaro, both weekly injections, are highly effective non-surgical options, with clinical trials showing up to 20.7% and 20.9% body weight reduction, respectively, when paired with healthy lifestyle changes. Wegovy is often more cost-effective for long-term management.

There are many ways people approach weight loss, and treatments that include surgical intervention have been popular for a number of years. But there are a few things to know about it before you make your decision.

Surgical weight loss treatment has become a popular method for shedding excess weight, but tried and true non-surgical weight loss can help you achieve your ideal body weight just the same.

Whether it's getting on top of your eating habits and making sure you stick to a healthy diet or making sure you exercise regularly, you're on the right path to your weight loss journey.

We get it: sometimes, no matter how much exercise you do or how much you reduce your calories, there often seems to be stubborn fat that remains.

So if you're looking for a little helping hand on your journey, we've compiled a comprehensive list of everything you need to know about surgical and non-surgical weight loss procedures and methods so that you can find the right path for you.

What factors influence weight loss?

If you're on a weight loss journey and finding it tricky to drop those extra pounds, it's common to start thinking about why you're holding on to that extra weight even when it feels like you're doing everything right.

But did you know there are a whole host of factors influencing your weight beyond diet and exercise programs?

Losing weight depends on several factors working together. Here are some important things to consider:

  • Calories: Here's one you probably already know, to lose weight, you need to eat fewer calories than you burn. When you consistently consume fewer calories, your body starts using stored fat for energy, leading to weight loss [1].
  • Healthy eating: Eating whole foods like fruits, veggies, lean proteins, and whole grains can help with weight loss [2]. Avoid processed foods, sugary drinks, and foods high in added sugars and unhealthy fats.
  • Exercise: Regular physical activity helps you burn calories and build muscle. Both cardio exercises, like running and strength training exercises, like weightlifting, are beneficial for weight loss.
  • Metabolism: Your metabolic rate, influenced by factors like age, genetics, and body composition, affects how your body burns calories. While it has a small impact on weight loss, building muscle through exercise can help boost metabolism [3].
  • Lifestyle choices: Portion sizes, meal planning, stress levels, sleep patterns [4], and sticking to a routine all play a role in weight loss.
  • Medical conditions and medications: Some medical conditions and medications can make weight loss more difficult. If you have any health conditions or take medications, consult a healthcare professional for personalised advice.
  • Hormone levels: Hormones can impact weight loss through appetite control, metabolism, and fat storage. Hormonal imbalances or changes, such as leptin, ghrelin, insulin, thyroid hormones, and cortisol, can affect these processes [5].
  • Emotions and mental well-being: Emotional eating and stress can affect weight loss. Managing stress, addressing emotional factors, and finding healthy ways to cope are important [6].

How much weight you lose and how quickly you achieve this weight loss are also impacted by your starting weight. This journey will take time, so make sure you're consistent and focused on your overall well-being.

Remember, weight loss is a complex process, and everyone is different. It's always a good idea to seek guidance from a healthcare professional or registered dietitian for personalised support on your weight loss journey.

What are the most common ways to approach weight loss?

If you're looking to lose weight, there are key approaches to consider. Firstly, eating a low-calorie diet aided by mindful eating and portion control is crucial.

Focus on a balanced diet that includes whole foods and minimises processed options. Finally, combining regular exercise with lifestyle changes like meal planning and stress management enhances weight loss efforts.

But sometimes, that can feel like it's just not shifting enough weight. That's why it's becoming increasingly popular to turn to certain surgical procedures that aid weight loss, such as the gastric balloon and endoscopic sleeve gastroplasty.

It's also increasingly common to use weight loss medications, Wegovy or Mounjaro, as these medications can help you lose weight and maintain your ideal weight, without the need for surgical intervention.

What are the eligibility requirements for weight loss surgery?

To be eligible for weight loss surgery in the UK, there are certain requirements you need to meet. These include [7]:

  • Body mass index (BMI): You will generally need to have a BMI of 40 or more. Alternatively, if your BMI is between 35 and 40 and you have an obesity-related condition like type 2 diabetes or high blood pressure that could improve with weight loss, you may also be considered eligible for weight loss surgery.
  • Previous weight loss attempts: You should have made attempts to lose weight through other methods like dieting and exercise, but haven't been successful in achieving significant or sustainable weight loss.
  • Long-term commitment: It's important to know that your weight loss journey won't end after surgery. You must be willing to commit to long-term follow-up after the surgery. This includes making healthy lifestyle changes and attending regular check-ups to ensure your progress and overall health.
  • Fitness and health: You should be fit and healthy enough to undergo the surgery, as determined by medical assessments.

It's important to note that eligibility criteria for weight loss surgery on the NHS can vary in different parts of England, so it's advisable to consult with your GP to understand the specific criteria in your area.

Additionally, while bariatric surgery is available privately, it can be costly. If you meet the NHS criteria, your GP can refer you to the Bariatric Service, where your suitability for surgery will be assessed.

What is the least invasive weight loss surgery?

Some less invasive options for weight loss surgery can give you that extra helping hand with your weight loss efforts; let's explore.

Gastric balloon

This weight loss procedure is quite gentle and doesn't require any incisions. They place a deflated balloon into your stomach and then fill it with saline to make you feel fuller and satisfied with smaller portions [8].

Gastric sleeve

This surgery involves removing a portion of your stomach through a small incision using a technique called laparoscopy. It also includes removing the part of the stomach that produces hunger hormones, which can help decrease your appetite [9].

Gastric band

In this procedure, they place a band around your stomach, creating a smaller pouch. It's done using a minimally invasive technique called laparoscopy. The gastric band can be adjusted later through a small port under your skin, which helps control your food intake and reduce your appetite [10].

These options are considered less invasive because they don't involve extensive incisions or rerouting of the intestines and minimise possible complications. It's important to remember that the suitability of these procedures varies for everyone, so it's best to consult with a healthcare professional to determine the most suitable option for you.

Can you also lose weight with a medical weight loss treatment?

If you're looking for additional support but want to avoid surgery, weight loss medication may be another suitable option. These prescription medications can help regulate appetite, reduce cravings, and support long-term weight loss when combined with healthy lifestyle changes.

In the UK, two of the most commonly prescribed medications are Mounjaro and Wegovy — both highly effective treatments known as GLP-1 receptor agonists.

Wegovy

Wegovy is a once-weekly injection containing semaglutide — a compound that mimics the natural hormone GLP-1 to regulate appetite, slow digestion, and help you feel fuller for longer.

Originally developed to manage blood sugar levels, it has since been approved in the UK as a weight loss treatment for adults with obesity or weight-related health concerns.

When used alongside healthy lifestyle changes, Wegovy has been shown to support meaningful and sustained weight loss. It's a convenient and effective option that can help reduce cravings, support healthier habits, and even improve blood sugar regulation, making it especially beneficial for people with conditions like PCOS.

Mounjaro

Mounjaro is also a weekly injection, however, its main active ingredient is tirzepatide — a dual-action compound that mimics the effects of both GIP and GLP-1 hormones to regulate appetite, improve blood sugar control, and promote fat loss. It is recognised for its powerful weight loss effects and has been approved in the UK for adults living with obesity or weight-related health conditions.

Like Wegovy, Mounjaro should be paired with healthy lifestyle changes to deliver significant and sustained weight loss. It works by reducing hunger, curbing cravings, and supporting better metabolic function. In comparison, however, Mounjaro doses tend to be a bit higher than other weight loss injections.

How much weight can you lose with non-surgical weight loss?

It is difficult to make an accurate prediction of the average weight loss using non-surgical weight loss methods, as there are so many different factors to consider. These could include:

  • Current weight
  • Age
  • Gender
  • Metabolism rate
  • Diet
  • Physical activity levels
  • Health conditions
  • Medical history
  • Medications

We can, however, provide insight into how these medications have helped our patients at Juniper to drop body weight within the first few weeks.

In clinical trials, patients on the highest possible dose of Wegovy lost up to 20.7% of their body weight [11], compared to 20.9% with Mounjaro at its highest dose [12] — showing that both can be highly effective when used consistently and with the right support.

While both incredibly effective, Wegovy can often be more accessible and cost-effective over time, making it a more favourable option for ongoing weight management. With Juniper, Wegovy is delivered as part of a complete programme that includes expert care, coaching, and tracking tools — to help you get the most from your treatment.

What are effective options for non-surgical weight loss?

Non-surgical weight loss procedures can be highly effective. Start by adopting a healthy eating plan with balanced nutrition and portion control. Engaging in regular physical activity, including both cardiovascular exercises and strength training, can help you achieve and maintain and healthy weight.

Plus, modifying behaviours, such as practising mindful eating and seeking support from weight loss programmes, might just give you that extra little push you need to start dropping the pounds.

Consulting healthcare professionals can provide personalised guidance, ensuring safe and effective weight loss strategies tailored to your needs. By combining these approaches, you can achieve sustainable results and improve your overall well-being.

Feel like you need an extra helping hand shedding some pounds, but are looking for something more holistic than surgery? The Juniper Programme provides comprehensive weight loss support, from prescription medication to clinical guidance, to connecting you with a community of like-minded women.

With plans tailored just for you, Juniper can help you lose weight for good.

Questions about medicated weight loss?
Not sure if weight loss medication is right for you? Concerned about side effects? Our team will explain how Juniper works and what to expect - so you can make the best choice for your health.
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Juniper patients lose an average of
23%
body weight
in 1 year
Data sourced from 373,000 weight tracker entries in the Juniper app
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80lbs
In one year patients at this start weight will be:
14lbs
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